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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Supportive Therapy in Oncology</journal-id><journal-title-group><journal-title xml:lang="en">Supportive Therapy in Oncology</journal-title><trans-title-group xml:lang="ru"><trans-title>Поддерживающая терапия в онкологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">3034-2473</issn><issn publication-format="electronic">3034-3178</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">61</article-id><article-id pub-id-type="doi">10.17650/3034-2473-2025-2-2-27-33</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Current state and prospects of using low-energy laser radiation for early radiation damage in the treatment of head and neck tumors</article-title><trans-title-group xml:lang="ru"><trans-title>Состояние и перспективы использования низкоэнергетического лазерного излучения ранних лучевых повреждений в лечении больных с опухолями головы и шеи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6835-5567</contrib-id><name-alternatives><name xml:lang="en"><surname>Alieva</surname><given-names>Sevil B.</given-names></name><name xml:lang="ru"><surname>Алиева</surname><given-names>С. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Sevil Bagaturovna Alieva.</p><p>24, Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>Севил Багатуровна Алиева.</p><p>115478 Москва, Каширское шоссе, 24.</p></bio><email>drsevil@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0183-4827</contrib-id><name-alternatives><name xml:lang="en"><surname>Zaderenko</surname><given-names>Igor A.</given-names></name><name xml:lang="ru"><surname>Задеренко</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24, Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4944-4035</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernykh</surname><given-names>Marina V.</given-names></name><name xml:lang="ru"><surname>Черных</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24, Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5231-9927</contrib-id><name-alternatives><name xml:lang="en"><surname>Fedoseenko</surname><given-names>Dmitriy I.</given-names></name><name xml:lang="ru"><surname>Федосеенко</surname><given-names>Д. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24, Kashirskoe Shosse, Moscow 115478.</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2025</year></pub-date><volume>2</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>27</fpage><lpage>33</lpage><history><date date-type="received" iso-8601-date="2025-07-01"><day>01</day><month>07</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-07-01"><day>01</day><month>07</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Alieva S.B., Zaderenko I.A., Chernykh M.V., Fedoseenko D.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Алиева С.Б., Задеренко И.А., Черных М.В., Федосеенко Д.И.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Alieva S.B., Zaderenko I.A., Chernykh M.V., Fedoseenko D.I.</copyright-holder><copyright-holder xml:lang="ru">Алиева С.Б., Задеренко И.А., Черных М.В., Федосеенко Д.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://stio.abvpress.ru/jour/article/view/61">https://stio.abvpress.ru/jour/article/view/61</self-uri><abstract xml:lang="en"><p>Low-energy laser radiation, having anti-inflammatory, biostimulating and analgesic effects, can be used for the prevention and treatment of radiation erythema of the skin and post-radiation mucositis.</p><p>We analyzed publications devoted to the use of laser therapy in patients with head and neck tumors undergoing radiation and chemoradiation therapy.</p><p>To date, there are no standardized parameters for the technique of using laser radiation for preventive and therapeutic purposes in case of radiation damage to the skin and mucous membrane. All this requires further study of the parameters of using low-energy laser therapy, both for the treatment of radiation complications in patients with head and neck tumors, and for the prevention of the frequency and severity of early and late radiation injuries.</p></abstract><trans-abstract xml:lang="ru"><p>Низкоэнергетическое лазерное излучение, обладая противовоспалительным, биостимулирующим и обезболивающим эффектами, может быть использовано для профилактики и лечения лучевой эритемы кожи и постлучевого мукозита. Мы проанализировали публикации, посвященные использованию лазерной терапии у пациентов с опухолями головы и шеи, проходящих лучевую и химиолучевую терапию.</p><p>На сегодняшний день нет стандартизированных параметров методики использования лазерного излучения с профилактической и лечебной целями при лучевых повреждениях кожи и слизистой оболочки. Необходимо дальнейшее изучение параметров применения низкоэнергетической лазерной терапии как для лечения лучевых осложнений у больных с опухолями головы и шеи, так и для профилактики частоты и выраженности ранних и поздних лучевых повреждений.</p></trans-abstract><kwd-group xml:lang="en"><kwd>radiation mucositis</kwd><kwd>radiation dermatitis</kwd><kwd>laser therapy</kwd><kwd>dose rate</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лучевой мукозит</kwd><kwd>лучевой дерматит</kwd><kwd>лазерная терапия</kwd><kwd>мощность дозы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Dunaev A.V. Physico-technical fundamentals of low-intensity laser therapy. Moscow: Lambert Academic Publishing, 2012. 286 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Дунаев А.В. Физико-технические основы низкоинтенсивной лазерной терапии. 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