Supportive Therapy in OncologySupportive Therapy in OncologyПоддерживающая терапия в онкологии3034-24733034-3178Publishing House ABV Press5210.17650/3034-2473-2025-2-1-44-57REVIEWSОБЗОРНЫЕ СТАТЬИFeatures of systemic therapy for treatment of brain metastases of kidney cancer (literature review)Особенности системной терапии при метастазах рака почки в головной мозг (обзор литературы)https://orcid.org/0000-0002-4335-8446SemenovD. V.СеменовД. В.
Russian Federation

Dmitry Vladimirovich Semenov 

7–9 Universitetskaya Emb., Saint Petersburg 199034 

56 Veteranov Prospekt, Saint Petersburg 198255 

Дмитрий Владимирович Семенов 

199034 Санкт-Петербург, Университетская наб., 7–9

198255 Санкт-Петербург, пр-кт Ветеранов, 56

sema.69@mail.ruhttps://orcid.org/0000-0002-9368-5517OrlovaR. V.ОрловаР. В.
Russian Federation

7–9 Universitetskaya Emb., Saint Petersburg 199034 

56 Veteranov Prospekt, Saint Petersburg 198255 

199034 Санкт-Петербург, Университетская наб., 7–9

198255 Санкт-Петербург, пр-кт Ветеранов, 56

https://orcid.org/0000-0003-4109-6451ShirokoradV. I.ШирокорадВ. И.
Russian Federation

27 Istra Village, Moscow Region 143423 

143423 Московская область, п. Истра, 27 

https://orcid.org/0000-0003-4494-1489KostritskyS. V.КострицкийС. В.
Russian Federation

27 Istra Village, Moscow Region 143423 

143423 Московская область, п. Истра, 27 

Saint Petersburg State UniversityФГБОУ ВО «Санкт-Петербургский государственный университет»Saint Petersburg City Clinical Oncological DispensaryСПб ГУЗ «Городской клинический онкологический диспансерMoscow City Oncological Hospital No. 62, Moscow Healthcare DepartmentГБУЗ г. Москвы «Московская городская онкологическая больница № 62 Департамента здравоохранения г. Москвы»150420252144570704202507042025Copyright ©; 2025, Semenov D.V., Orlova R.V., Shirokorad V.I., Kostritsky S.V.Copyright ©; 2025, Семенов Д.В., Орлова Р.В., Широкорад В.И., Кострицкий С.В.2025Semenov D.V., Orlova R.V., Shirokorad V.I., Kostritsky S.V.Семенов Д.В., Орлова Р.В., Широкорад В.И., Кострицкий С.В.https://creativecommons.org/licenses/by/4.0https://stio.abvpress.ru/jour/article/view/52

The article presents a review of modern methods of systemic therapy in patients with brain metastases of kidney cancer based on analysis of up-to-date literature data which support multimodal treatment strategy including systemic therapy, radiotherapy and/or surgical treatment. The main goal of drug therapy is to slow down metastatic process progression, increase survival of these patients. Currently, the optimal approach to treatment of brain metastases of renal cell carcinoma has not been established.

В статье представлен обзор современных методов системной терапии у больных с метастазами в головной мозг рака почки на основании анализа современных данных литературы, которые свидетельствуют в пользу мультимодальной стратегии лечения, включающей системную терапию, лучевую терапию и/или хирургическое вмешательство. Основная цель лекарственной терапии – замедление прогрессирования метастатического процесса, повышение показателей выживаемости у данной категории пациентов. В настоящее время оптимальный подход к лечению метастазов в головной мозг при почечно-клеточном раке не определен.

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